Reduction of Inflammation
Mesenchymal stem cells have anti-inflammatory properties and can help reduce inflammation in damaged tissues of the shoulder, which can alleviate pain and stiffness.
Mesenchymal Stem Cell (MSC) Transplantation
Treatment of Rotator
Cuff Injury
Background information
What do we know today about rotator cuff injury?
Rotator cuff tendinitis is a common injury in which the tendons of the rotator cuff, a group of muscles and tendons that surround the shoulder joint, become inflamed and painful. Here are some things we know about this injury today:
Symptoms: Symptoms of rotator cuff tendinitis include shoulder pain, especially when lifting the arm overhead, arm weakness, difficulty sleeping on the affected side, and popping or snapping sensation in the shoulder joint.
Diagnosis: The diagnosis of rotator cuff tendinitis is made through a combination of medical history, physical examination, and imaging tests such as X-ray or magnetic resonance imaging (MRI).
Prevalence: The prevalence of rotator cuff tendinitis in the general population is estimated to be around 2-5%. However, this number increases significantly in older age groups, affecting up to 20% of individuals over 70 years old.
Laterality: Rotator cuff tendinitis can affect both the right and left shoulders, although some studies suggest that the dominant shoulder (usually the right in most people) has a higher predisposition to develop this injury.
The causes of rotator cuff tendinitis can vary, but they are generally attributed to a combination of factors. Some common causes include:
Traumatic injuries
An acute injury, such as a fall or a direct blow, can damage the tendons of the rotator cuff and cause inflammation.
Overuse
Rotator cuff tendinitis can also occur as a result of repetitive arm use in activities that involve lifting heavy objects, throwing, swimming, painting, or any activity that involves repetitive shoulder movements.
Aging
As we age, the tendons of the rotator cuff can weaken and lose elasticity, which increases the risk of tendinitis.
Genetic factors
Some individuals may have a genetic predisposition to develop rotator cuff tendinitis.
Chronic inflammation
Chronic inflammation in the brain may play a role in the development of Parkinson's disease.
Postural problems
Poor posture can contribute to tension in the muscles and tendons of the shoulder, increasing the risk of tendinitis.
Systemic diseases
Certain diseases such as diabetes, rheumatoid arthritis, and gout can increase the risk of developing rotator cuff tendinitis.
In general, rotator cuff tendinitis is a common condition that can be caused by a combination of factors. Early diagnosis and treatment are important to prevent complications and promote quick recovery.
Scientific studies
Scientific research on the treatment of rotator cuff injury using mesenchymal stem cells is ongoing
Rotator cuff tendinitis is a common condition that causes pain and reduced shoulder function. Conventional treatment includes physiotherapy, anti-inflammatory medications, and, in some cases, surgery. However, mesenchymal stem cell therapy has emerged as a potentially promising alternative.
Mesenchymal stem cells are cells that have the ability to differentiate into various cell types and possess anti-inflammatory and regenerative properties. Several studies have demonstrated that mesenchymal stem cells can reduce inflammation and improve tissue repair.
Mesenchymal stem cells are cells that have the ability to differentiate into various cell types and possess anti-inflammatory and regenerative properties. Several studies have demonstrated that mesenchymal stem cells can reduce inflammation and improve tissue repair.
Here are some relevant statistics regarding research on this topic:
- A study published in the journal Stem Cells Translational Medicine in 2018 evaluated the safety and efficacy of mesenchymal stem cell therapy in patients with rotator cuff tendinitis. The results showed a significant improvement in shoulder pain and function after treatment, with no serious side effects reported.
- A study published in the Journal of Shoulder and Elbow Surgery in 2016 examined the effectiveness of mesenchymal stem cell therapy in combination with surgical repair of the rotator cuff in patients with chronic rotator cuff tendinitis. The results showed that mesenchymal stem cell therapy significantly improved shoulder function and quality of life in the patients.
- A study published in the journal Stem Cell Research & Therapy in 2017 evaluated the safety and efficacy of mesenchymal stem cell therapy in patients with rotator cuff tendinitis. The results showed that mesenchymal stem cell therapy significantly improved shoulder pain and function compared to the control group that received conventional treatment.
- A study published in the Journal of Shoulder and Elbow Surgery in 2014 examined the effects of mesenchymal stem cell therapy in combination with surgical repair of the rotator cuff in patients with rotator cuff tendinitis. The results showed a significant improvement in shoulder function and quality of life in the patients after treatment.
- A study published in the journal Orthopedics in 2018 compared mesenchymal stem cell therapy with platelet-rich plasma (PRP) therapy in patients with rotator cuff tendinitis. The results showed that both treatments were effective in improving symptoms of rotator cuff tendinitis, but mesenchymal stem cell therapy had a significantly higher success rate compared to PRP therapy.
Summary of Benefits for Rotator Cuff Injury
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